39 issued patents and 11 pending applications owned by Cascade Biosystems, Inc.
Restrictase Cascade Exponential Amplification (RCEA) is a revolutionary DNA detection technology which has the potential to completely disrupt the current polymerase chain reaction (PCR) market. Unlike PCR, which copies DNA segments, RCEA uses a series of enzymatic reactions to detect the target DNA. RCEA is low cost, has high sensitivity and near-perfect specificity, and can be performed quickly in the field. Early application development and proof of concept experiments have been successful and are documented in at least two publications. There are widespread potential applications: bacterial, pathogen, or cancer detection; agricultural or veterinary diagnostics; food safety testing; environmental testing; genetic testing; forensics; and more.